<span>This study aimed to analyse the effect of work-family conflict on work stress and the moderating role of social support and perceived organisational support in the effect of work-family conflict on work stress. The type of this research is explanatory research. Data collection techniques were questionnaires and variable measurement techniques based on a Likert scale</span><span>. The population is 100 female nurses who have families in Malang City</span><span lang="EN-US">, Indonesia</span><span>. Data </span><span>were analysed using inferential statistics and a moderation test using Smart PLS. The study's results revealed that work-family conflict had a significant effect on work stress; social support moderated the effect of work-family conflict on work stress; Perceived organisational support had a moderating role in the effect of work-family conflict on work stress.</span><span> <span lang="EN-US">Nurses began to have difficulty balancing family and work roles. They are trying to overcome various problems such as increased working hours, excessive workload, difficult working conditions and the pandemic. Therefore, the role of social support and organizational support felt by nurses will reduce the impact of work-family conflict on work stress.</span></span>