Job involvement has emerged as an important aspect effects towards employee performance and productivity. A review of the literature shows that personality traits are considered important factors for person's decision to involve in work. Particularly, this study aims to examine how extraversion and agreeableness effect on job involvement. Further, the author also examined influence of collectivism on job involvement. Research data collected from 239 registered nurses in public hospitals at Palembang city. The analytical tool used to test the effect of the independent variable extraversion (X1), agreeableness (X2), and collectivism (X3) on job involvement (Y) with multiple regression statistical method. The results of the analysis show that extraversion, agreeableness, and collectivism the most important predictors of job involvement.