The study investigates the influence of the entrepreneurship education and family towards the motivation of the students of YKPN Business School to do the entrepreneurship both partially and simultaneously. The entrepreneurship motivation was the dependent variable and the independent variables were entrepreneurship education and family. This population study was conducted by having the questionnaires to 126 students of YKPN Business School who had passed the entrepreneurship subject and were taking the subject when this study was being done. Then, the data was analyzed using multiple regression method. The result of the study showed that entrepreneurship education impacted significantly positive towards the entrepreneurship motivation showed by t-count 3.238 with significance level 0.002. Family also had positive and significant effect towards the entrepreneurship motivation with t-count 3.238 and significance level 0.000. Simultaneously, entrepreneurship education and family positively affected entrepreneurship motivation.