<p><em>Hospital Business is ever-changing and dynamic, there are many variables that could affect it business process and hospital sustainability, one of them is Patient Payment Method. Meanwhile in Indonesia, the country with big population, they Universal Coverage System (Jaminan Kesehatan Nasional – BPJS Kesehatan) starts to make a change towards Hospital Business wave.</em></p><p><em> </em></p><p><em>This research highlighted are to find is there any significant effect of Universal Coverage System towards Hospital business process.</em></p><p><em> </em></p><em>We believes that Hospital adaptability towards change in customer payment methods will give impact to It business process</em>