<p>This study aims to examine effect of entrepreneurial orientation, either directly or indirectly on small medium enterprises (SMEs) performance . This study also examine effect of information acquisition mediate relationship between entrepreneurial orientation dan firm performance.</p><p>This study is quantitative research through survey techniques in data collecting process. Survey was done at SMEs in Banyumas district by distributing questionnaires directly to  SMEs owners. Sampling was conducted using purposive sampling technique. Results obtained 150 samples of data collection that can be used to test the research hypothesis. Data was analized by path analysis to test the research model.</p><p>The results show that entrepreneurial orientation plays an important role to improve SMEs’performance. Entrepreneurial orientation in running businesses motivate SMEs to acquire information to improve business performance. Information acquisition plays an important to formulate a business strategy that is different from its competitors. This study contributes to provide an understanding of the interrelationships entrepreneurial orientation dan acquisition of information in improving SMEs’performance.</p>